ZEST
- 66 participants
- 8 sites in New Zealand
New Zealand Eplerenone Aortic Stenosis Trial. A randomised double-blinded placebo controlled trial to investigate the effects of long-term treatment with the aldosterone receptor antagonist eplerenone on the left ventricular mass and volume with magnetic resonance imaging in patients with asymptomatic moderate to severe aortic stenosis. Sample size: 66 patients. Timeframe: 36 months.